Thomson Reuters Analysis Finds High Market Potential in Stage II Antidepressants

July 9th, 2014

It’s been 25 years since the launch of Prozac exploded the anti-depressant drug market, but a new three-part analysis of the drug development pipeline, patent filing and sales forecast data that we’ve released today found that, despite a steady downward trend antidepressant sales, global pharmaceutical companies are aggressively setting up partnership arrangements and rallying behind new Stage II pipeline drugs to target depression.

Their goal: Reaching the 350 million people worldwide who have depression, 50 percent of whom go untreated.

Our analysis dives into the behind-the-scenes industry activity (pipeline development, partnership activity, new patents, scientific literature publications) in the antidepressant space to spotlight some of the following key trends:

  • Alkermes & Roche Claim the 3 Most Notable Antidepressants in Development: There are three notable drugs currently in Phase II clinical trials, all with mechanisms of action that differ significantly from traditional SSRI and SNRI type antidepressants on the market: Alkermes’ ALKS-5461 and Roche’s RG-7090 and RG-1578.  Each of these is forecast by Thomson Reuters to surpass $100 million in sales by 2019.
  • Development and Distribution Deals Heat Up: Licensing deals between pharmaceutical developers indicate a sustained interest in cracking the antidepressant market.  The three largest antidepressant related deals currently on the table are between Otsuka/H.Lundbeck for Abilify and Brexpiprazole; Dainippon Sumitomo/Takeda for Latuda; an Otsuka/Bristol-Myers Squibb for Abilify.

  • China Takes the Lead in Antidepressant Patent Activity: Since 2003, U.S. antidepressant patents have dropped 50%, while China’s has spiked 124%. The most active single company in this space is H. Lundbeck A/S, a Danish firm, and GlaxoSmithKline, a British multinational.
  • Worldwide Sales Forecasts Declining: Antidepressant drug sales dropped 5.5 billion (from 15 billion in 2003 to 9.5 billion in 2012) and are projected to drop another 2.5 billion by 2019.  The decline is being driven by the rapid rise of generics and a movement away from using drugs as a first line of treatment for depression.

To view infographic illustrating the analysis, click here.

To read a report on the challenges and opportunities in the depression drug market, click here, or here to learn more about the dominant scientific research surrounding the condition.

Laura Gaze, Senior Marketing Manager, IP Solutions Life Sciences , , ,

USPTO Cancels Washington Redskins’ Trademark Registration

June 19th, 2014

The United States Patent and Trademark Office has canceled the Washington Redskins trademark registration, calling the football team’s name “disparaging to Native Americans.”

A 1992 suit over the trademark was thrown out on a technicality, since some of the plaintiffs had waited too long after turning 18 to file. Since then, at least a dozen new trademark applications involving the word “Redskins” have been denied, the most recent a filing for hog rinds that the board declared “derogatory” and “offensive.” But this case, officially known as Blackhorse v. Pro-Football Inc., which was first filed in 2006, put the already-existing registrations on the line.

Federal trademark law does not permit registration of trademarks that “may disparage” individuals or groups or “bring them into contempt or disrepute.” The ruling pertains to six different trademarks associated with the team, each containing the word “Redskin.”

Laura GazeLaura Gaze, Director, IP Solutions: While the ruling does not mean that the Redskins have to change the name of the team, it does affect whether the team and the NFL can make money from merchandising. The team can still use its name, but this decision means they lose “presumed” ownership of it. Therefore, in subsequent court fights, the franchise has to prove through use they own the mark. That will ultimately limit the team’s legal options when others use the logos and the name on T shirts, sweatshirts, beer glasses and license plate holders, so it’s a major headache, and could result in a name change. There will be appeals here, but this is certainly a landmark decision.

Laura Gaze, Senior Marketing Manager, IP Solutions Trademarks , , , , ,

Global Innovation Spikes to Pre-Recession Levels

May 15th, 2014

We’ve released our latest State of Innovation report today that analyzes global patent filing data over the last 5 years. The 2014 edition of the study, which tracks global patent volumes of 12 bellwether industries, charts hottest growth areas, the impact of emerging markets and nascent hotbeds of new economic growth, finds that the overall rate of innovation growth is now at its highest level since the Great Recession.

Following are some of the report’s key findings:

  • Biggest Innovation Gains Since End of Recession: Total, worldwide patent volume increased 26% over the last year, with 11 of the 12 technology areas studied showing increases. All but one of the 11 gainers had double-digit growth.
  • Automotive Safety, Energy Exploration and Smart Kitchen Appliances Drive Largest Gains: The Automotive, Petroleum, and Domestic Appliances technology areas had the greatest year-over-year increases, with each logging a 35% jump in worldwide patent volume over the prior period. Domestic Appliances ranked among the top three leaders for the second consecutive year. Safety-related innovation saw the greatest gains in the Automotive sector; while the Petroleum sector was driven by petroleum and gas exploration, drilling and processing.
  • Emerging Markets & Academic Contributions on Upswing: Increased activity from China and Russia emphasizes the focus on innovation in these regions, as do increased activity on the part of universities and research institutions. More of such entities made it into the Top 10 regional lists than any year in the past.
  • Computing & Peripherals Continue to Lead the Global Pack: The technology area with the largest overall global patent volume continues to be Computing & Peripherals, for the fifth consecutive year, with over 300,000 inventions over the past year. That’s more than double the innovation activity of the next nearest technology area: Telecommunications. All subsectors within Computing & Peripherals showed positive gains, a first since this report’s inception.

To read the full report, http://ip.thomsonreuters.com/sites/default/files/2014stateofinnovation.pdf

Laura Gaze, Senior Marketing Manager, IP Solutions Innovation , ,

Can the Patent Box Make or Break Pfizer’s AstraZeneca Takeover?

May 1st, 2014

The British government’s incentive program designed to convince companies to locate research-and-development teams in the U.K. may be at the center of Pfizer’s planned takeover of AstraZeneca.

“The United Kingdom has created attractive incentives for companies to manufacture products and maintain and protect intellectual property, and we have seen that capital and jobs have followed these types of incentives,” Pfizer CEO Ian Read said in a Monday-morning statement designed to woo Astra shareholders (via the WSJ).

According to the Journal:

“When the patent box has been fully phased in by 2017, it will mean qualifying companies pay 10% tax on their profits derived from U.K.-held patents, compared with the current rate of 21% (the rate will fall to 20% in April 2015) […] A combined Pfizer and AstraZeneca would be incorporated in the U.K. (but listed in New York), Mr. Read said Monday, and would therefore be better placed to take advantage of the patent-box tax break on any new drugs developed in the U.K.”

Laura GazeLaura Gaze, Director, Thomson Reuters: The incentives under this new tax regime, which companies have been navigating through for the better part of two years, seem as though they are doing exactly as they were intended. But will this new structure derail Pfizer’s plan? This is an extremely complicated deal with many moving parts, so we may not have answers to these questions for a while, but it’s clear the patent box is set to be a very significant item that may decide many corporate agendas in the years to come.

Laura Gaze, Senior Marketing Manager, IP Solutions Innovation, Patents , , , , ,

Would a Ruling Against Aereo Curb American Innovation?

April 30th, 2014

A major Aereo investor said a Supreme Court ruling against the New York-based streaming company could have serious repercussions on American innovation.

Media mogul Barry Diller told CNN that a Supreme Court decision to shut Aereo, a company that streams local broadcast television to customers’ computers, phones and tablets for $8 per month, would have “profound effects on the development of technology.”

“It’s almost like saying, ‘what if there was no telephone?,” Diller told CNN. “If [the Supreme Court justices] stop it—which they very well may—I don’t think it’s the end of any world because we’ll not really know, but I think … if it stops, it will have profound effects on the developments of technology.”

Laura GazeLaura Gaze, Director, Thomson Reuters: It’s an interesting debate. On one hand, Diller obviously has a vested interest, but he does make a reasonable point. While ABC, NBC, Fox and CBS, accuse Aereo of unlawfully transmitting their copyrighted TV content without paying for licenses, Aereo argues that its service is the legal equivalent of selling customers an antenna and a DVR. It does give one pause to wonder what really is the difference? Ultimately, this will come down to the Court’s interpretation of “public performance” under U.S. copyright law, but should Aereo get shut down, it may deal a serious blow to the evolution of streaming platforms.

Laura Gaze, Senior Marketing Manager, IP Solutions Innovation , , ,

Apple-Samsung Battle Comes to the Final Stand

April 29th, 2014

Tuesday is set to be the day of reckoning in the smartphone patent wars.  That’s because Apple and Samsung’s $2 billion patent dispute is set to reach its conclusion, with closing arguments slated to wrap up the latest infringement case between the two powerhouses.

Each side will get two hours to in a San Jose courtroom, where an Apple victory would allow the iPhone maker to seek a court order barring U.S. sales of earlier models of Samsung phones equipped with Android features. Two years ago, Apple was awarded a $930 million decision over Samsung.  Despite the monetary sum, Apple failed to win an order barring sales of infringing Samsung phones.

Laura GazeLaura Gaze, Director, Thomson Reuters: The first time a decision was handed down between these two companies, it reverberated throughout the entire industry. Now, with Apple possibly being able to bar the sales of infringing phones, the entire market could stand to change. A decision for Apple would significantly shake up the landscape in this space, and it would set a precedent that could open Samsung up to even more vulnerability down the road. Stay tuned to the IP Solutions blog, where we’ll have more as the decision comes down.

Laura Gaze, Senior Marketing Manager, IP Solutions Patents , , , ,

Thomson Reuters Study Finds a Global Imbalance in Diabetes Research Funding

April 24th, 2014

The diabetes epidemic continues to surge with the disease affecting an estimated 382 million people worldwide. But a large gap exists in the research and funding, making understanding these ebbs and flows pivotal in continuing to understand the landscape. That’s why we’ve released a new analysis today that identifies the top 34 global funders of diabetes research.

The analysis was conducted by Thomson Reuters ScienceWatch analysts and found that the U.S. National Institutes of Health is the leading funding organization with 13,436 acknowledgements, followed by the National Natural Science Institute of China with 3,354 acknowledgements, and the Juvenile Diabetes Research Foundation (JDRF) with 2,547 acknowledgements. Other top 35 funders include government agencies such as the Canadian Institutes of Health Research; the Ministry of Education, Culture, Sports, Science and Technology of Japan; and the American Heart Association, as well as global pharmaceutical giants such as Novo Nordisk and Pfizer.

However, several regions that are strongly impacted by the disease were notably absent from the list. According to the International Diabetes Federation, an estimated 20 million people live with the disease in Africa, and the continent has the highest global rate of mortality, but no African organizations were listed among the top funding agencies. Africa-based researchers did contribute to 1,581 diabetes-related papers.

In addition, regions of Southeast Asia, the Middle East, and India are similarly afflicted, but their research output does not yet measure up. Sixty five million of India’s 1.2 billion people are affected by diabetes, but no India-based organizations have yet emerged among the 35 most-prolific funders.

To view the infographic that further illustrates this regional imbalance, visit http://sciencewatch.com/sites/sw/files/sw-article/media/sw-diabetes-infographic.pdf

Laura Gaze, Senior Marketing Manager, IP Solutions Innovation , , ,

China and India Lead the Innovation Charge Inside the G20

April 9th, 2014

We’ve released a new study, “The Research and Innovation Performance of the G20”, that tracks citation patterns in scientific research papers and the patent portfolios of the G20 over a 10-year period. The report provides detailed data on total patent and research citation volumes, as well as deep-dive analysis into subject-matter expertise and overall global influence, in order to give a glimpse into the future of the worldwide innovation landscape.  Following are the key data points:

  • Toppling the Giants? The world share of scientific research citations from the US has fallen from 33 percent in 2003 to 27.8 percent in 2012, while the EU has declined 3 percent over the same period.  Additionally, while domestic patent volume has grown steadily in the US by an annual rate of 2 percent from 2003 to 2012, the Chinese rate of growth dwarfs that figure (29 percent). Also of note, American innovation accounts for 56 percent of all US patent applications, down from 63 percent in 2003, and seven of the top ten patenting companies in the US have headquarters in Asia.
  • Peer-Reviewed Papers Spike in China and India, Brazil Declines: Chinese peer-reviewed papers accounted for 14 percent of the world’s share in 2012, up from 5.6 percent in 2002 and < 0.5 percent at the start of the 1980s, respectively. India produced twice as many published research papers in 2012 as it did in 2003, but the country did experience its first year-over-year dip in 10 years from 2011 to 2012.  Brazil, despite a dramatic increase in total output of peer-reviewed research between 2003 and 2012, accounted for just 2.7 percent of the world’s share and saw slight declines in output between 2011 and 2012.

  • Australia, France and Great Britain Show Strongest Gains in Scientific Influence Among Developed Nations: Senior research producers, such as Australia, France and Great Britain, recorded significantly higher rates in their production of highly cited research papers between 2002 and 2011, while the U.S. was the only major developed nation to lose ground over the same period.

For more information and to read the full report, visit http://sciencewatch.com/sites/sw/files/images/basic/research-innovation-g20.pdf

Below is our infographic on the report (click here to enlarge):

Shift in Influence of G20 Nations

Explore more visuals like this one on the web’s largest information design community – Visually.

Laura Gaze, Senior Marketing Manager, IP Solutions Brand Protection, Trademarks , , , , ,

Thomson CompuMark Study Finds Brands are Flocking to China, Brazil, India, Mexico, Taiwan

March 27th, 2014
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Thomson CompuMark Study Finds Brands are Flocking to China, Brazil, India, Mexico, Taiwan
What are the top consumer markets in the world right now?  According to our latest analysis, State of Trademarks: Global Insights on Trademark Trends, which we released this Thursday, the United Kingdom, Germany, Russia and Canada aren’t even in the top 10.  In their place: China, Brazil, India, Mexico and Taiwan.
Thomson Reuters CompuMark, which maintains the world’s largest database of trademark filing data, discovered this significant shift by analyzing global trademark volumes over the course of 2013. The goal was to determine which jurisdictions are receiving the most attention from multinational brands.  We found that new, emerging markets have replaced the old standbys in the branding world:
China Leads the World in Total Trademark Volume: China leads the world with over 860,000 new trademarks published in 2013.  It is followed by the U.S., Brazil, South Korea, Turkey and Japan.
India, Mexico and Taiwan Replace UK, Germany and Canada on Top 10 List: When studying each unique mark (regardless of the number of classes in which it is filed),the UK, Germany and Canada dropped from the list of top 10 global trademark registrars and are replaced by India, Mexico and Taiwan. Noticeably missing from the top 10 list was one of the four largest emerging and developing markets, Russia.
Brazil Is Fastest-Growing Consumer Market: Among the top 10 trademark registrars in 2013, those showing the sharpest year-over-year growth in new trademark filings are Brazil (53 percent), South Korea (23 percent) and Turkey (18 percent).
For more information and to download the full report, visit [LINK

What are the top consumer markets in the world right now?  According to our latest analysis, State of Trademarks: Global Insights on Trademark Trends, which we released this Thursday, the United Kingdom, Germany, Russia and Canada aren’t even in the top 10.  In their place: China, Brazil, India, Mexico and Taiwan.

Thomson Reuters CompuMark, which maintains the world’s largest database of trademark filing data, discovered this significant shift by analyzing global trademark volumes over the course of 2013. The goal was to determine which jurisdictions are receiving the most attention from multinational brands.  We found that new, emerging markets have replaced the old standbys in the branding world:

  • China Leads the World in Total Trademark Volume: China leads the world with over 860,000 new trademarks published in 2013.  It is followed by the U.S., Brazil, South Korea, Turkey and Japan.
  • India, Mexico and Taiwan Replace UK, Germany and Canada on Top 10 List: When studying each unique mark (regardless of the number of classes in which it is filed),the UK, Germany and Canada dropped from the list of top 10 global trademark registrars and are replaced by India, Mexico and Taiwan. Noticeably missing from the top 10 list was one of the four largest emerging and developing markets, Russia.
  • Brazil Is Fastest-Growing Consumer Market: Among the top 10 trademark registrars in 2013, those showing the sharpest year-over-year growth in new trademark filings are Brazil (53 percent), South Korea (23 percent) and Turkey (18 percent).

For more information and to download the full report, visit trademarks.thomsonreuters.com/industry-resources/industry-research/special-reports

Laura Gaze, Senior Marketing Manager, IP Solutions Brand Protection, Trademarks , , ,

Quote: Human Element Integral to Innovation

March 21st, 2014

Speaking at the ad:tech event in Sydney, Australia, Owen Rogers, senior partner at Palo Alto-based design firm IDEO, said the human element of the innovation process is too important to be ignored, and unfortunately, many executives do just that when deciding on a strategy:

“There are three elements to any problem – technical, feasible [business] and the human piece. Everybody typically forgets the human piece, or they devalue it, thinking the technical or business piece has to be overcome first and foremost.”

Laura Gaze, Senior Marketing Manager, IP Solutions Innovation , , , ,